Day cream with retinol and antihistamines is a product that combines retinol, a vitamin A derivative that can smooth wrinkles and fade dark spots, and antihistamines, medications that can soothe redness and itchiness. This product should be used in the morning, as it can hydrate and protect the skin. Apply a thin layer to clean and dry skin, avoiding the eyes. Use sunscreen with SPF 30 over the cream, as retinol can increase sun sensitivity.